Beta Testing

Aminobutyric Acid; Gamma-Aminobutyric Acid

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Potential Risk IndexTM:


About:

Food additives -> Flavoring Agents Flavouring Agent: FLAVOURING_AGENT

Gamma-Aminobutyric Acid is a naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid ( GABA ), converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA -A and GABA -B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission.

Scientific References :
1. PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/119


Safety and Hazards (UN GHS):

1. Causes skin irritation (H315)
2. Causes serious eye irritation (H319)
3. May cause respiratory irritation (H335)

Potential Health Concerns For:

2. Bradycardia ( PubMed ID:1451572 )
3. Catalepsy ( PubMed ID:6771794 )
4. Catatonia ( PubMed ID:2823166 )
5. Cocaine-Related Disorders ( PubMed ID:15135161 )
6. Epilepsy ( PubMed ID:19474175 )
7. Hemiplegia ( PubMed ID:3683725 )
8. Hypertension ( PubMed ID:10524271 )
9. Hypotension ( PubMed ID:1451572 )
10. Manganese Poisoning ( PubMed ID:18771689 )
11. Movement Disorders ( PubMed ID:2727012 )
12. Schizophrenia ( PubMed ID:18757185 )
13. Seizures ( PubMed ID:9030893 )
14. Status Epilepticus ( PubMed ID:1969357 )
15. Substance Withdrawal Syndrome ( PubMed ID:10690749 )
16. Tachycardia ( PubMed ID:2541852 )

Potential Health Benefits For:

1. Drug-Related Side Effects and Adverse Reactions ( PubMed ID:6872331 )
2. Glucose Metabolism Disorders ( PubMed ID:25456265 )
3. Stomach Ulcer ( PubMed ID:28456544 )
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